Author

Max Hess

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Open access Oct 2026

3D Iterative Immunofluorescence Imaging on Whole-Mount Samples

Multicellular organization relies on reciprocal interactions between molecular events, such as gene expression and protein state, and higher-scale properties, such as spatial patterning and tissue architecture. Understanding these processes requires methods that enable quantitative measurements at subcellular resolutio...

M. Wyss, Max Hess, Shayan Shamipour et al. · Bio-protocol · 0 citations

Open access Sep 2026

Multiplexed embryo profiling links cellular state to zygotic genome activation in single cells

The cell cycle phase is the major source of variability in transcription within a division cycle, and combining this with the analysis of key transcription factors and chromatin modifier state enables accurate prediction of transcriptional output during zygotic genome activation in individual cells.

Max Hess, M. Wyss, Edlyn Wu et al. · Nature Communications · 0 citations