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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Max Land

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Open access Oct 2026

Random mtDNA mutagenesis maps genotype-phenotype associations across metabolic contexts and lineages

Mitochondrial DNA (mtDNA) mutations cause inherited disease, accumulate with age, and recur in tumors, yet their effects remain unresolved because existing models interrogate one engineered allele at a time. We developed mtDIVE, a random C→T mutagenesis platform for pooled mitochondrial forward genetics in human epithe...

Amir Giladi, Ron Baik, Chih-Yao Chung et al. · 0 citations
Open access Jul 2026

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development

A pro-tumorigenic IL-1β/IL-6 signaling circuit mediated through local macrophages and fibroblasts is identified that unleashes the full oncogenic potential of a cancer driver activated at the PIN stage, with implications for TME-specific targeted therapeutics in early-stage disease.

Young-Sun Lee, Jimmy L. Zhao, Agnieszka Chryplewicz et al. · 0 citations

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