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Maximilian Frosch

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Open access Aug 2026

USP8 controls proteostasis pathways in B cells and multiple myeloma.

Ubiquitin-specific protease 8 (USP8) plays a pivotal role in the regulation of endosomal and lysosomal trafficking and is critically involved in the pathogenesis of various tumor entities. USP8 represents a vulnerability gene in multiple myeloma (MM), suggesting a functional role in the B- and plasma cell compartment....

Almut Dufner, Fabien Théry, G. Monaco et al. · 1 citation
Open access Jul 2026

Coding agents author interpretable single-cell embedding models from the literature

C coding agents can author single-cell embedding models directly from the literature, which are competitive in biological quality with conventional, foundation-model, and program-informed baselines, batch-robust by construction and reproducible across runs, complementing data-driven embeddings.

Niklas Brunn, S. M. Krißmer, Maximilian Frosch et al. · 0 citations

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