Author

Maximilian M. Schaefer

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Open access Sep 2026

A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion.

Pancreatic ductal carcinoma (PDAC) is characterized by a highly immunosuppressive, extracellular matrix-rich microenvironment, yet tumours display marked heterogeneity1-4. This raises the question of whether immune resistance is a global tumour property or is organized within spatially restricted niches. Here, using Pe...

C. Falcomatà, Maximilian M. Schaefer, Bhavya Singh et al. · Nature · 0 citations