Author

Maximilien Burq

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Open access Sep 2026

Rapid Mechanistic Bridging of an Alzheimer’s Disease Plasma Protein Staging Panel Across Brain Proteomics Cohorts

Re-mining legacy mass spectrometry data for disease-relevant proteoforms, combined with pre-structured datasets, can accelerate evaluation of emerging blood-based biomarkers against neuropathological and molecular features of disease.

Charles C. Kim, Meghan Kerrisk Campbell, Maximilien Burq et al. · bioRxiv · 0 citations

Open access Aug 2026

Single-cell foundation models benefit from cross-modal training: adding proteomics data beats parameter scaling

It is shown that with the right training recipe, heterogeneous proteomics data can improve the learned representations of single-cell RNAseq samples, demonstrating strong out-of-distribution generalization and suggesting that multimodal pretraining is a promising path toward more informative biological foundation model...

Maximilien Burq, Peter Cimermancic, Charlie Kim et al. · bioRxiv · 1 citation