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Md. Istiaq Ansari

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Open access Aug 2026

SPIDER: spatially integrated denoising via embedding regularization with single cell supervision

SPIDER is introduced, a semi-supervised framework that leverages independently generated, annotated single-cell RNA-seq (scRNA-seq) references to guide ST denoising, providing a generalizable solution for robust ST data denoising.

Md. Istiaq Ansari, Muhtasim Noor Alif, Wei Zhang · Bioinformatics · 2 citations