Review
Sep 2026
Lipid flip-flop in biological membranes: through the lens of TMEM16F
The biology of regulated transmembrane phospholipid flip-flop mediated by lipid scramblases is examined, using TMEM16F as a prototypical model to illustrate core molecular mechanisms, physiological functions, pathological implications, and emerging pharmacological opportunities.
Shan Z. Ke, Augustus J. Lowry, Maria A. Gonzalez Torres et al.
· Physiological Reviews · 0 citations