Author

Mehmet Köse

2 papers indexed here

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Case report Aug 2026

A novel FLNA p.Pro2469Ser variant is associated with impaired T and NK cell function and immune dysregulation

Findings indicate that the FLNA p.Pro2469Ser variant identified in a pediatric patient presenting with recurrent infections and inflammatory manifestations is associated with altered immune-cell signaling, disturbed cortical cytoskeletal organization, and immune dysregulation.

Ş. Erdem, A. Kısaarslan, M. B. Acar et al. · Immunologic research · 0 citations

Aug 2026

Pediatric cystic fibrosis is associated with type 3 immune response

Pediatric CF is associated with selective alterations in circulating type 3 and regulatory immune responses, characterized by increased IL-22-producing lymphocyte populations, reduced plasma IL-17 A concentrations, and increased numbers of CD3⁺IL-10⁺ cells.

Tugba Nur Gur, Z. B. Azizoğlu, Yesim Haliloğlu et al. · Molecular Biology Reports · 0 citations