Mehul Arora

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning.

Mitochondria are four-dimensional (4D: x, y, z, and time) organelles essential for cellular function. Characterizing their 4D phenotypic landscape across diverse cellular states requires both 4D imaging and analytical frameworks. We present MitoSpace, a self-supervised deep learning model trained without labels on tera...