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Author

Mei Chen

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2 papers indexed here

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Open access Aug 2026

CaMK4 drives pathogenic Th17 cell response via the STAT3/RORγt axis in psoriasis

Psoriasis is a chronic inflammatory skin disease driven by dysregulated immune responses, particularly those mediated by pathogenic Th17 cell response; however, the key intracellular signaling molecules that specifically regulate Th17 cell pathogenicity in the skin remain incompletely defined. Here, we showed that...

Hui-Yao Ge, Xin-Wen Zhang, Mei Chen et al. · 0 citations
Open access Sep 2026

Integrated bioinformatics and experimental validation reveal lucanthone as a promising therapeutic agent targeting core genes in psoriasis.

Psoriasis is an immune-mediated chronic inflammatory skin disease driven by epidermal hyperproliferation and cutaneous immune dysregulation, yet lacks reliable diagnostic biomarkers. Here, we identified 14 core genes with excellent diagnostic value (AUC = 0.996), which were abnormally upregulated in psoriatic lesions,...

Xin-Wen Zhang, Shan-Ru Yang, Mei Chen et al. · 0 citations

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