Sep 2026
Vitamin K3 attenuates STING-agonist-induced signaling and imiquimod-induced psoriasis-like inflammation.
Cytosolic DNA sensing through the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) axis is an important component of innate host defense, whereas sustained pathway activation has been implicated in inflammatory and autoimmune diseases. Although several potent STING inhibitors are in preclinical devel...
Zu-Yi Jin, Zhen Huang, Yi-Qin Zhang et al.
· Biochemical Pharmacology · 0 citations