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Author

Mei-Qi Lin

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Review Aug 2026

The niche-metabolism axis: reprogramming tumor-associated macrophages for precision immunotherapy.

Tumor-associated macrophages (TAMs) critically modulate solid tumor progression and immunotherapy resistance, yet their profound context-dependent heterogeneity defies the traditional M1/M2 dichotomy. In this review, we propose the 'niche-metabolism axis' framework, deconstructing the tumor microenvironment into dynami...

Li-Jun Zhao, Xu-Yun Li, Wen-Yue Liu et al. · 0 citations

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