Causal Effects of Circulating Sex Hormone Levels on the Risk of Endometriosis: A Two-Sample Mendelian Randomization Study
Background:Endometriosis is a chronic, estrogen-dependent, immune-modulated disorder with unclear causal contributions from circulating sex hormones. Understanding whether hormone levels directly influence risk may guide prevention and targeted therapies. To evaluate the causal effects of circulating sex hormones—estra...