Mei-Ya Liu

Polydopamine-assisted architecture-enabled local delivery of miR-34a-loaded M1 macrophage extracellular vesicles and curcumin from an injectable thermogelling hydrogel for triple-negative breast cancer

The engineered preorganized hydrogel showed stronger overall retention of both miR-34a and curcumin, higher intracellular miR delivery in MDA-MB-231 cells, greater suppression of viability and clonogenicity, stronger apoptosis and G0/G1 cell-cycle redistribution, lower residual invasion, and deeper downregulation of BC...