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Author

Melanie G. Kirkpatrick

2 papers indexed here

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Open access Oct 2026

Astroviruses use mucus secretion as a novel form of viral egress

It is demonstrated that mucus secretion is a novel form of non-lytic enteric viral egress, which deepens the understanding of the astrovirus replication cycle and may hold clues to understanding its pathogenesis.

Natalie Pedicino, Melanie G. Kirkpatrick, Michelle Ann Pablo et al. · 1 citation
Open access Oct 2026

Pan-Coronavirus Protease Engagement and Differentiated Pharmacology of Antiviral Candidate CMX990

COVID-19 highlighted the need for antivirals that can be rapidly deployed against both current and future coronavirus threats. CMX990 is a clinical stage coronavirus main protease (Mpro) inhibitor bearing a unique trifluoromethoxymethyl ketone warhead. Here, we broadly evaluate its pan-coronavirus target engagement, an...

N. G. R. Dayan Elshan, Karen C. Wolff, L. Riva et al. · 0 citations

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