Melinda Meyers

Biomechanical strain alters the microRNA cargo of primary myogenic cell-derived extracellular vesicles associated with a differentiation phenotype

Extracellular vesicles (EVs) are membrane-bound vesicles that regulate intercellular signaling by transporting cellular cargo including RNAs, proteins, and lipids. In recent years, EVs have emerged as promising biologic therapeutics for musculoskeletal repair, recapitulating many of the benefits of mesenchymal stromal...