A bifunctional RNase H protein supports DNA replication and transcription in nucleus-forming Chimalliviridae phages
Jumbo bacteriophages of the Chimalliviridae family replicate their genomes within a proteinaceous phage nucleus that spatially segregates viral DNA replication and transcription from translation. While the phage nucleus protects viral DNA from host defenses, it also imposes unique constraints on genome replication and...