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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Men Fan

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2 papers indexed here

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Open access Sep 2026

Extracellular vesicle proteins monitor and interfere with CLDN18.2-targeted CAR-T cell and antibody therapies against gastrointestinal cancers

Claudin 18.2 (CLDN18.2)-targeted CAR-T cell and antibody therapies show promise against gastrointestinal cancers, but biomarkers predictive of long-term benefit and therapeutic sensitization strategies are needed. Here we show that proteins carried by circulating extracellular vesicles (EVs) can reflect and influence t...

Chang-Song Qi, Ming-Yang Ma, Kai-Jie Liang et al. · 0 citations
Sep 2026

Z526 alleviates cancer cachexia-induced muscle and adipose inflammatory injury in vitro via suppression of macrophage ROS-associated MAPK/NF-κB activation.

Cancer cachexia is a multifactorial syndrome characterized by skeletal muscle wasting and adipose tissue atrophy. Our previous study showed that Z526 alleviated cancer cachexia-associated symptoms and reduced circulating inflammatory cytokine levels, suggesting that its effects may involve modulation of macrophage-asso...

Li-Xuan Pan, Xiao-Fan Gu, Jun-Jie Fu et al. · 0 citations

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