Phillygenin protects against lipopolysaccharide-induced acute lung injury by acting as a PXR agonist via NF-κB inhibition
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening conditions with substantial mortality and limited targeted therapies. The pregnane X receptor (PXR) has emerged as a promising therapeutic target for inflammatory diseases, though its role in ALI remains underexplored. This stud...