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Author

Meng-De Wu

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Sep 2026

ACSL5 drives pancreatic ductal adenocarcinoma by suppressing mitophagy and enhancing ferroptosis resistance via the JAK1-STAT1-OASL axis.

It is revealed that targeting mitophagy represents a potential strategy for ACSL5-high PDAC, and its overexpression is significantly associated with shorter patient survival and high diagnostic accuracy, suggesting robust diagnostic potential.

Jing-Jing Dong, Meng-Ting Dai, Yi-Ming Zhou et al. · 0 citations

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