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Author

Meng-Han Shi

2 papers indexed here

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Open access Sep 2026

SS-31 Attenuates Lipopolysaccharide-Induced Injury in HK-2 Renal Tubular Epithelial Cells via SIRT3-Mediated Regulation of Mitochondrial Metabolism

Background: The mitochondrial-targeting peptide Elamipretide (SS-31) has shown protective effects against sepsis-associated acute kidney injury (S-AKI). Therefore, we investigated the mechanism underlying its effects on lipopolysaccharide (LPS)-induced injury in renal tubular epithelial cells, with a focus on mitochond...

Xiang-Wei Wu, Meng-Han Shi, Min Sun et al. · 0 citations
Open access Sep 2026

Dendritic-cell-targeting adeno-associated virus as potent cancer vaccine carriers

The clinical efficacy of therapeutic cancer vaccines is critically limited by the inefficient in vivo delivery of tumor antigens to dendritic cells (DCs), the key regulators of T-cell immunity. To address this issue, we developed a dendritic-cell-targeting adeno-associated virus (AAV) vector through ra...

Xin Wei, Xiang Li, Li-Xia Qi et al. · 0 citations

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