Sep 2026
IL-17A Induces Chondrocyte Senescence via the STAT3-OPA1-mtROS Axis in Temporomandibular Joint Osteoarthritis.
OBJECTIVES To elucidate the pathogenic mechanisms underlying interleukin-17A (IL-17A) induced chondrocyte senescence in TMJ-OA and provide preclinical evidence supporting IL-17A as a novel therapeutic target for TMJ-OA. METHODS We established a TMJ-OA mouse model using unilateral anterior crossbite (UAC) to investiga...
Meng-Qi Zhu, Chun-Yan Zhang, Yang-Yang Zhang et al.
· Oral Diseases · 0 citations