Sep 2026
AMPK/mTOR/ULK1-mediated cytotoxic autophagy synergizes with apoptosis to drive the anti-endometrial cancer efficacy of platinum nanoclusters.
Nano-Pt exerts potent anti-tumor effects in EC by orchestrating a lethal crosstalk between mitochondria-mediated apoptosis and cytotoxic autophagy via the AMPK/mTOR/ULK1 signaling axis, highlighting its immense potential as a safe and effective nanotherapeutic.
Meng-Jun Zhang, Jia-Lin Wang, H. Yue et al.
· Biomaterials Advances · 0 citations