Association of Intestinal Barrier Damage and Mucosal Microbiota Dysbiosis with the TLR4/NF-κB Pathway in High-Salt Diet-Induced Hypertensive Rats
Background: A high-salt diet is a major risk factor for hypertension, but the role of the intestinal mucosal microbiota and the dysfunction of the intestinal barrier remain to be explored. Methods: Wistar rats were fed a normal diet (OF) and a high-salt diet (HSF) for 33 days to establish hypertension. Serum NO and TNF...