From Retrieval to Reasoning: Agentic Mechanism Prediction from Cell Painting Profiles
PhenoAIR is proposed, a reliability-aware multi-agent framework that maintains a candidate-centric evidence memory and performs controller-guided refinement over phenotype- and mechanism-side evidence and outperforms representation-matching and LLM-based baselines across all settings.
Jia-Yuan Chen, Botao Yu, Tian-Yu Liu et al.
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