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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Meng-Xuan Jia

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Open access Sep 2026

Glutathione functionalized selenium nanoparticles suppress colorectal cancer cell growth with mitochondrial dysfunction and mitophagy related remodeling

Glutathione functionalization may improve the physicochemical and biological performance of selenium nanoparticles; however, the effects of glutathione-functionalized selenium nanoparticles (GSH-SeNPs) on colorectal cancer (CRC) cells remain insufficiently defined. In this study, GSH-SeNPs were synthesized and characte...

Meng-Xuan Jia, Xue-Min Feng, Zi-Yi Bai et al. · 0 citations
Open access Sep 2026

Multi-parameter optimization of a novel anti-TROP2 MMAE antibody-drug-conjugate for solid tumor therapy

TROP2 is expressed in many epithelial tumors including breast and lung cancers. It is a clinically validated ADC target based on approvals of sacituzumab govitecan for triple-negative breast cancer and datopotamab deruxtecan for HR-positive, HER2-negative breast cancer. An alternative cytotoxic approach was previousl...

Laurence Fayadat-Dilman, Andrew B. Waight, Lauren Adams et al. · 0 citations

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