Organoids have emerged as powerful
in vitro
models that bridge the gap between traditional two-dimensional cultures and
in vivo
studies. Over the past decade, advances in stem cell biology and extracellular matrix (ECM) engineering have enabled the establishment of organoids that partially recapitulate the stru...
Ovarian cancer develops within a biological environment that changes substantially with age. Beyond chronological aging, progressive alterations in genome maintenance, telomere integrity, epigenetic regulation, mitochondrial function, metabolism, inflammation, and immune surveillance can reshape the cellular and tissue...
Yu-Bo Zhang, Yue Han, Pin-Zhi Hou et al.· Frontiers in Pharmacology· 0 citations
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