Tumor-immune cell crosstalk critically shapes the progression of non-small cell lung cancer (NSCLC), yet the mechanisms underlying exosome-mediated immune suppression remain incompletely understood. Here, we identify a previously unrecognized exosomal lncRNA-mediated immunoregulatory axis targeted by the natural compou...
Qin-Feng Zhou, Yang Guo, Lei Wang et al.· Pharmacological Research· 0 citations
N6-methyladenosine (m6A), the most abundant internal RNA modification in eukaryotic cells, has emerged as a critical regulator of antiviral host defense. Increasing evidence indicates that m6A functions beyond conventional post-transcriptional regulation by dynamically coordinating the magnitude, timing, and duration o...
Xian-Feng Hui, Shuo-Xiang Gao, Shi-Huan Ding et al.· Frontiers in Immunology· 0 citations
SYD can alleviate intestinal inflammation, inhibit apoptosis, and protect the intestinal barrier in the CD model, and mechanistic studies indicated that TRDMT1 and TLR4 were involved in the protective effects of SYD against CD-like colitis.
Yonghao Deng, Jing Wang, Meng-Yi Li et al.· International Immunopharmaco...· 0 citations
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