A Broad-Spectrum Tumor-Penetrating Peptide WKASC: Design, Screening, and Platform Development for Cancer Therapy.
Conventional cancer therapies are often limited by inadequate drug accumulation in tumors, drug resistance, and systemic toxicity. Cell-penetrating peptides (CPPs) offer a promising strategy to enhance intracellular drug delivery. In this study, we designed a novel tumor-penetrating peptide, P3 (sequence: Trp-Lys-Ala-S...