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Author

Mengyu Chai

2 papers indexed here

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Open access Oct 2026

Inhibiting MD2 activates AMPK-dependent PPARγ/NOX4 signaling to attenuate mitochondrial oxidative stress and relieve pulmonary hypertension.

AIMS Pulmonary hypertension (PH), a severe vascular disorder, is closely associated with chronic inflammatory states and oxidative stress. Myeloid differentiation protein 2 (MD2), a key co-receptor of Toll-like receptor 4 (TLR4), is well established in mediating various inflammation-driven pathologies. However, its rol...

Jun Chen, Meng-Yu Chai, Yi-Chen Liu et al. · 0 citations
Case report Open access Aug 2026

Pulmonary sarcomatoid carcinoma in the anterior mediastinum mimicking thymic carcinoma with rapid widespread metastases

Rationale: Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive subtype of non–small-cell lung cancer. Marked histologic heterogeneity, nonspecific imaging findings, and limited representation in small biopsy specimens can cause diagnostic error, particularly when a pulmonary lesion abuts the anterior mediast...

Linru Zhong, Mengyu Chai, Hongyu Lin et al. · 0 citations

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