Sep 2026
HIF-2α-mediated PLVAP suppression in gCap drives immune infiltration in chronic hypoxia-induced pulmonary edema.
The HIF-2α-PLVAP axis is defined as a gCap-specific regulatory mechanism governing endothelial barrier integrity and inflammatory modulation under chronic hypoxia, providing a mechanistic proof-of-concept for PLVAP restoration as a potential therapeutic strategy.
Ye Lyu, Ya-Kun Gu, Yue Wang et al.
· Cellular Signalling · 0 citations