Review
Open access
Sep 2026
Lipid droplet organized metabolic vulnerabilities in melanoma: from the MITF low state to ferroptosis sensitization
A major conclusion from this review is that the MITF low state is not uniformly ferroptotic; rather susceptibility depends upon a balance among lipid sequestration, membrane remodeling, oxidative metabolism, antioxidant defenses and cellular iron content.
Meng-Zhen Chen, Yi Wu, Mu-Xin Zhao
· Frontiers in Molecular Biosc... · 0 citations