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Author

Meng Zhu

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Aug 2026

Mannose-modified tobacco mosaic virus-mediated macrophage regulation inhibits pulmonary fibrosis progression.

A mannose-modified tobacco mosaic virus nanoparticle is developed, which targets and reprograms profibrotic macrophages to inhibit IPF and establishes plant viral nanoparticles as a macrophage reprogramming strategy with therapeutic potential for organ fibrosis.

Jiaodan Jin, Ren Xu, H. Fu et al. · 0 citations
Sep 2026

A 4-Arm polyethylene-glycol-based multivalent galactoside disrupts Pseudomonas aeruginosa biofilm and restores antibiotic susceptibility.

Results indicate that 4-Arm-PEG-Gal significantly disrupts mature biofilm and is specifically recognized by the lectin LecA, and compared to the use of antibiotics alone, the combination of 4-Arm-PEG-Gal and TOB reduces antibiotic usage by 75% and additionally eradicates 73% of the bacteria within the biofilm.

Chen-Xiao Wan, Xiaoyan Ju, Mei-Yun Ma et al. · 0 citations

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