Author

Mengfan Jiao

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Aug 2026

TBX15 increases ferroptosis to overcome sorafenib resistance via HERC5-mediated cGAS ISGylation in hepatocellular carcinoma.

The study identified a significant association between low TBX15 expression and sorafenib resistance in HCC and established the TBX15-cGAS/STING axis as a key regulator in HCC pathobiology.

Hui Yuan, Mengfan Jiao, Ye Sun et al. · Free Radical Biology & Medic... · 0 citations