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Menghui Fan

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Aug 2026

Computational simulation to improve the activity of a heterologous feruloyl esterase secreted by Bacillus subtilis.

Feruloyl esterases (FAEs) release ferulic acid from plant cell walls but suffer from low efficiency and poor stability. A putative FAE (FAE-BSaf) from Bacillus safensis was expressed in Bacillus subtilis via a non-classical pathway, exhibiting optimal activity at 55 °C and pH 8.5. Using AlphaFold3 modeling and ΔΔG pred...

Menghui Fan, Jiayi Zhong, Si-Yuan Liu et al. · 0 citations

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