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Mercedes Grima-Terrén

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Open access Oct 2026

An integrative transcriptomic atlas of ALS and aging skeletal muscle defines shared and distinct molecular programs of degeneration.

An integrated single-nucleus transcriptomic atlas of skeletal muscle is generated, identifying transcriptionally distinct condition-specific myonuclear states, including disease-responsive programs within synaptic myonuclei at the neuromuscular junction, that are shared or distinct between the two conditions.

Mercedes Grima-Terrén, Megan K. Rommelfanger, Silvia Campanario et al. · 0 citations

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