Méria Saci

Delayed Diagnosis of Advanced CYLD Cutaneous Syndrome with Extensive Multifocal Scalp Cylindromas and Spiradenomas: A Case Report

Background: CYLD cutaneous syndrome (CCS), formerly known as Brooke–Spiegler syndrome, is a rare autosomal dominant genodermatosis caused by pathogenic variants in the CYLD gene. It is characterized by the development of multiple skin adnexal tumours, including cylindromas, spiradenomas, and trichoepitheliomas, which m...