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Author

Merrilee Needham

2 papers indexed here

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Open access Sep 2026

Identity-by-descent to resolve reduced penetrance and advance gene discovery in neurodegenerative disease.

Advances in sequencing technologies have transformed human genetics and accelerated disease gene discovery. Yet a causal mutation remains to be identified for many families with an inherited disease. Incomplete penetrance, genetic heterogeneity, and limited family history can complicate the binary classification of fam...

L. Henden, Sandrine Chan Moi Fat, Andrew N. Smith et al. · 0 citations
Open access Apr 2026

Altered sensorimotor neuroplasticity in subacute patients with non-severe burn injury

Abstract Background Burn injuries affect the central nervous system, and evidence suggests they induce changes in cortical excitability related to motor dysfunction. The current study investigated markers of neuroplasticity in the motor cortex and motor performance in the subacute period following burn injury. Methods...

Grant Rowe, Mark W. Fear, D. Edgar et al. · 0 citations

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