Author

Merve Eskici

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Open access Aug 2026

Association of AP-1/c-Jun with IL-6 and IL-8 expression in hepatocellular carcinoma: attenuating effects of metformin in vitro

Investigating the effects of metformin on key inflammatory cytokines involved in hepatocellular carcinoma progression, as well as on the expression of c-Jun, a key subunit of the AP-1, led to a significant reduction in the levels of IL-6 and IL-8 in HepG2 cells compared to control group.

Tuğba Soydaş, Merve Eskici, M. Tunçdemir · Interdisciplinary Medical Jo... · 0 citations