Author

Mesfer Al Shahrani

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Open access Aug 2026

Structure-Based Identification of HFS764 as an Inhibitor of the HIF-1α–p300 Interface in Hypoxic Renal Cell Carcinoma

HFS764 disrupts the HIF-1α–p300 interface and suppresses hypoxia-driven signaling in ccRCC, supporting the use of transcriptional complex inhibition as a promising therapeutic strategy.

Mesfer Al Shahrani · Discover medicine · 0 citations