Author

Mete Hakan Karalök

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Open access Aug 2026

The FGF23/α-Klotho Axis in Postmenopausal Osteoporosis: Associations with Bone Mineral Density and Diagnostic Discrimination

Background: Fibroblast growth factor 23 (FGF23) and α-Klotho are key regulators of mineral metabolism and bone homeostasis; however, their combined diagnostic value in postmenopausal osteoporosis remains incompletely understood. This study investigated the associations of serum FGF23, α-Klotho, and the FGF23/α-Klotho r...

Mete Hakan Karalök, N. Mısırlıoğlu, Oznur Dundar Akin et al. · Journal of Clinical Medicine · 0 citations

Review Open access Sep 2026

Organelle-Selective Autophagy in Cancer Immunotherapy: Mitophagy and Nucleophagy-Related Nuclear Quality Control as Regulators of Tumor–Immune Interactions

Organelle-selective autophagy is an important regulator of tumor adaptation, immune signaling, and therapeutic resistance. By directing specific intracellular cargos to lysosomal degradation, selective autophagy pathways determine whether organelle damage is eliminated or remains available to innate immune sensors. In...

Ayhan Bilir, Berna Yıldırım, Mete Hakan Karalök · International Journal of Mol... · 0 citations

Review Open access Sep 2026

Female Reproductive System Assembloids in Health and Disease

In just over a decade, in vitro modeling of the female reproductive tract has advanced from planar monolayers of immortalized cells to self-organizing epithelial organoids and, most recently, to increasingly complex multicellular and multicompartment 3D models, including assembloids that combine organoids with addition...

Mete Hakan Karalök, Burcu Biltekin, Turgay Barut et al. · Cells · 0 citations

Review Open access Aug 2026

Age and Follicle-Stimulating Hormone as Variables Independently Associated with Serum Anti-Müllerian Hormone in Women Attending a Tertiary Gynaecology Clinic: A Retrospective Cross-Sectional Study Using Censoring-Aware Modelling

Objective: Anti-Müllerian hormone (AMH) is the most widely used biochemical marker of ovarian reserve, but its associations with other reproductive hormones are usually examined one hormone at a time and without accounting for values reported at the assay floor. This study examined the associations between serum AMH an...

Mete Hakan Karalök, Bağnu Dündar, Ayhan Parmaksız et al. · Metabolites · 0 citations

Open access Jul 2026

Age-Adjusted Associations Between Routine Systemic Inflammatory Markers and Anti-Müllerian Hormone in Reproductive-Age Women: A Retrospective Cross-Sectional Study

Background: Anti-Müllerian hormone (AMH) is widely used as a marker of ovarian reserve and is strongly influenced by chronological age. Although inflammation has been implicated in ovarian aging and follicular dysfunction, whether routinely measured peripheral inflammatory markers provide additional information regardi...

Mete Hakan Karalök, Bağnu Dündar, Ayhan Parmaksiz et al. · Biomedicines · 0 citations