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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Mhaned Oubounyt

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4 papers indexed here

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Open access Oct 2026

Concurrent de novo inference of cell types and gene regulatory networks with NetMap

NetMap is presented, a pipeline that jointly infers cell-level GRNs and clusters cells based on shared regulatory programs, combining state-of-the-art single-cell autoencoders and explainable artificial intelligence methods that outperforms existing methods on synthetic data with a known ground-truth GRN and is able to...

A. Hartebrodt, Mhaned Oubounyt, G. D. de Almeida et al. · 0 citations
Open access Oct 2026

Integrating network medicine and foundation models reveals cell-type-specific regulatory alterations in Alzheimer’s disease

Abstract Alzheimer’s disease is a complex neurodegenerative disorder characterized by progressive cognitive decline and neuroinflammation. Although its molecular hallmarks are well documented, cell-type-specific mechanisms driving gene dysregulation remain elusive. While single-cell RNA sequencing resolves cellular sta...

Andrea Álvarez-Pérez, Alejandro Rodríguez González, Jan Baumbach et al. · 0 citations
Preprint Sep 2026

Quantum Optimisation for Protein-Protein Interaction Network Alignment

Protein-protein interaction (PPI) network alignment combines topological and sequence information to identify conserved modules across species, but global alignment remains challenging: heuristics sacrifice optimality, while exact methods lack scalability. We model the alignment as a weighted maximum common induced sub...

M. Stahl, Robert J. Banks, M. Traube et al. · 0 citations
Open access Aug 2026

Clifti-GPT: privacy-preserving federated fine-tuning and transferable inference of foundation models on clinical single-cell data

Foundation models have demonstrated immense value for scRNA-seq analysis, but their fine-tuning or inference on heterogeneous, privacy-sensitive clinical cohorts is governed by strict data protection policies, which often prohibit centralization. We introduce Clifti-GPT, a privacy-preserving federated framework based o...

Mohammad Bakhtiari, M. Elkjaer, Ali Oğuz Can et al. · 0 citations

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