Author

Mi-Na Lee

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Open access Oct 2026

Integrated UHPLC-MS/MS Metabolomics, Network Pharmacology, Molecular Docking, and Experimental Validation Reveal the Anti-Inflammatory Mechanisms of Pyrus pyrifolia Peel Extract

Pyrus pyrifolia (Burm. f.) Nakai has long been utilized in traditional East Asian medicine to treat respiratory disorders, fever, cough, and inflammatory conditions. This study aimed to evaluate the antioxidative and anti-inflammatory effects of P. pyrifolia. UHPLC-MS/MS analysis revealed that P. pyrifolia contained 22...

Ducdat Le, D. Rhyu, Mi-Na Lee · Antioxidants · 0 citations

Aug 2026

Characterization of a plasma-derived protein fraction from Magallana gigas and its modulatory effects on lipopolysaccharide-induced inflammatory responses in HT-29 cells.

A plasma-derived protein fraction (MG-1) was partially purified from the hemolymph of the Pacific oyster, Magallana gigas, and its potential modulatory effects on lipopolysaccharide (LPS)-induced inflammatory responses were evaluated in HT-29 intestinal epithelial cells. SDS-PAGE analysis revealed two major protein ban...

Seung-Yub Song, Sung-Ho Lee, Dae-Hun Park et al. · International Journal of Bio... · 0 citations

Aug 2026

New glycosides from the leaves of Lansium domesticum: Isolation, structural elucidation, and anti-inflammatory activity.

Integrated network pharmacology and molecular docking analyses suggested that the active glycosides may exert their anti-inflammatory effects through the modulation of multiple inflammation-related targets and signaling pathways, providing a plausible mechanistic basis for their observed anti-inflammatory activity.

H. Q. Nguyen, Hien Thi Tran, L. T. Thao et al. · Carbohydrate Research · 0 citations