sFRP2, a member of the secreted frizzled-related protein family, is an extracellular protein characterized by a cysteine-rich domain and a netrin-like (NTR) domain. By modulating ligand availability, receptor selection, and microenvironmental signal integration, sFRP2 exerts highly context-dependent biological effects....
Xiao-Ping Luo, Mian Li, Yi Huang et al.· Frontiers in Cell and Develo...· 0 citations
Hyperuricemia (HUA) is a common metabolic disorder with rising global prevalence and is closely linked to gout, chronic kidney disease, and cardiovascular complications. Current Western drugs are limited by single-target mechanisms and adverse effects, whereas traditional Chinese medicine (TCM) is proposed to offer mul...
Hong Li, Si-Qi You, Xiao-Ping Luo et al.· Frontiers in Pharmacology· 0 citations
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