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Miao-Miao Han

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Open access Sep 2026

Prediction of Ocular Toxicity of Prostaglandin F2α Analogs Based on Local Computational Models: Superiority over Global Models and Experimental Validation

Results show how a localized modeling approach is better able to capture structure–toxicity correlations among chemically similar compounds and highlight the critical need for rigorous impurity management in latanoprost products, particularly regarding 15(S)-latanoprost.

Xin-Yi Lu, Li Ren, Chen Wang et al. · 0 citations

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