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Miaomiao Wen

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Open access Aug 2026

E3 Ubiquitin Ligase MDM2 Contributes to Proliferation, Migration/Invasion, Epithelial-Mesenchymal Transition, and Glycolytic Reprogramming in Lung Cancer via Ubiquitinating and Degrading MYH11 Protein.

Lung cancer remains the leading cause of cancer-associated death, and aerobic glycolysis is a key hallmark of cancer. Ubiquitination is a post-translational modification involved in the regulation of lung cancer progression. The aim of this study was to investigate E3 ubiquitin ligase mouse double minute 2 (MDM2) and i...

Yan-Feng Fang, Wen-Ting Wu, Miaomiao Wen et al. · 0 citations

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