Irradiated CD19 chimeric antigen receptor YTS cells retain antitumor activity and offer a scalable alternative to autologous CAR-T therapy.
E engineered YTS cells are positioned as a novel, scalable, and cost-effective "off-the-shelf" immunotherapy platform suitable for treating refractory leukemias and lymphomas and future studies will be required to assess safety and to explore applicability to autoimmune diseases and solid tumors.