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Michael Houghton

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Jul 2026

Abstract B095: Targeted inhibition of SLC2A5 prevents tumour growth and metastasis

Two derivatives of a known GLUT5 inhibitor that prevent fructose transport in the micromolar to nanomolar range are identified using in-silico molecular docking and in vivo tumour xenograft experiments to determine the mechanism dictating essential fructose functions in cancer.

J. Groenendyk, K. Sahu, Lorne D. Tyrell et al. · 0 citations

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