Author

Michael J. Frank

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#diffusion models Oct 2026

Acute stress reorganizes pregenual cingulate and subthalamic coupling to approach-avoidance decisions in remitted depression

Major depressive disorder (MDD) is highly recurrent, and psychosocial stress is a central precipitant of relapses. Daily choices require weighing potential rewards against costs, a process disrupted in MDD that may contribute to relapse. Here, we tested whether a psychosocial stressor affects neural and computational m...

Manuel Kuhn, Nadja Rita Ging-Jehli, Emma Holly Palermo et al. · bioRxiv (Cold Spring Harbor... · 0 citations

#reinforcement learning Open access Sep 2026

Modeling decision dynamics disentangles working memory, cognitive control and reinforcement learning and reveals clinical differences.

Various neurocognitive processes contribute to reinforcement learning (RL) and decision making, requiring careful task designs and computational modeling to disentangle them. People rely on capacity-limited working memory (WM) to rapidly and flexibly adapt behavior during learning, together with slower incremental RL p...

Krishn Bera, Alexander Fengler, Megan A. Boudewyn et al. · PLoS Computational Biology · 0 citations