Open access
Sep 2026
MADCAP: isolation of novel nAb-naïve AAV capsids from metagenomic data
This work establishes metagenomic mining as a powerful tool for accelerating AAV capsid discovery, identifying isolates with favorable tissue tropisms and resistance to broadly neutralizing antibodies.
E. Lyashenko, Tess Torregrosa, Alexandra B. Ysasi et al.
· Journal of Virology · 0 citations